OSTEOINDUCTIVE
Demineralized bone matrix (DBM) contains various biologically active bone morphogenic proteins (BMPs), which are among the osteoinductive components of bone. BMPs promote the differentiation of mesenchymal cells into chondrocytes and osteoblasts, leading to new bone formation. Human allograft. More than 20 BMPs (including BMP-2 and BMP-7) have been identified in bone tissue so far. Each batch of tissue used in production is tested with a validated bioassay to measure its osteoinductive potential.
 
OSTEOCONDUCTIVE - OSTEOGENIC
The cortico-spongy bone fragments in the DBM crush mixture provide an osteoconductive scaffold for bone growth. When mixed with fresh bone marrow aspirate or autograft from the patient, the paste and crush mixture becomes osteogenic.
 
NO CARRIER
This product is derived entirely from human allograft bone tissue. A unique processing method was invented to eliminate the need for exogenous organic carriers that have no bioactivity or biological function. The use of 100% human DBM helps minimize dilution of the osteoinductive potential of the graft It is possible.
 
EASY TO USE
The paste and crush mixture is malleable and flowable. These formulations do not wash off easily and can be used to grow autologous spongy or cortico-spongy grafts.
 
TRUSTWORTHY
Cortical bone is demineralized using a validated process proven to provide viral inactivation. The product is also final sterilized using a validated gamma irradiation process. Berkeley Advanced Biomaterials Inc. is accredited by the American Association of Tissue Banks (AATB).  ;Donor tissue is recovered, screened, tested, and processed according to standards established by the AATB. Donor screening includes a physical examination, interviewing a person who knows the donor, review of available medical records, and review of autopsy findings when appropriate. FDA and CDC People who are considered to be at high risk for AIDS or hepatitis are excluded from donation. Using FDA-licensed test kits in a CLIA-certified laboratory, the serum sample taken from the donor has been subjected to hemodilution examination and tested for HIV-1, HIV-2, hepatitis B and C, and syphilis. It has been tested to be non-reactive. DBM is produced from ground cortical bone. It is intended to be used in filling bone defects and gaps. DBM may be an alternative for patients who do not want to have an extensive open procedure or for whom an open procedure carries a high risk.